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MedEquine is a topical anti-microbial treatment for horses against summer itch, girth itch, saddle sores, ringworm, papilla warts, insect bites, parasitic irritations and bacterial, fungal and viral infections of the skin by Empire Pharmaceutical Inc.
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> Home > Clinical Studies > University of Florida's Gainesville Study Double-blinded, Placebo Controlled Study During the Summer and Fall of 2005 , two highly respected veterinary dermatologists at the University of Florida College of Veterinary Medicine, Gainesville, Drs. Rosanna Marsella and Lisa Akucewich, conducted a double blind investigational study to determine the clinical efficacy and tolerability of topical MedEquine® for the treatment of bacterial skin infections in horses. In this prospective, double blinded, placebo controlled clinical trial MedEquine® gel significantly decreased the severity of clinical lesions in horses diagnosed with bacterial skin infections after a 4-week treatment. Twenty horses were enrolled in the trial. At the beginning and at the end of the trial (days 0 and 28), horses were evaluated clinically and cytologically for the presence of infection. Owners scored pruritus on a weekly basis. On days 0 and 28 the investigator assigned a clinical score that was the sum of scores assigned to different body regions. On day 28 a significant decrease of investigator clinical and owners' pruritus scores was observed in the MedEquine® group while the vehicle group did not show any significant change. At the end of the trial, none of the horses in the MedEquine® group required additional therapy while 4/10 horses in the vehicle group required systemic therapy to resolve the infection. MedEquine® gel was well tolerated in all cases. It is concluded that MedEquine® is an effective and safe therapy for the topical management of bacterial skin infections in horses. Fig. Investigator's clinical scores on days 0 and 28.  N.B. - the lesions of the MedEquine® treated animals progressively improved while the skin lesions of the Vehicle/Placebo treated animals continued to worsen. Fig. Owner's pruritus scores were assigned on a weekly basis during the trial.  N.B. - the pruritis ( itchiness ) of the MedEquine® treated animals progressively improved while the pruritis of the Vehicle/Placebo treated animals remained the same. Extracted from University of Florida's Gainesville Study
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